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Wolfson School of Mechanical and Manufacturing Engineering
ULTRATOME: Ultrasonic microtome blade for improved histological section quality
Next generation histology to support stratified medicine diagnoses will need to increase the volume of samples processed, in order to perform screening exercises and to provide more intensive sampling for precise diagnoses. Automation is key to this, we plan to develop a novel ultrasonic microtome blade that will be capable of sectioning difficult materials easily, with controlled thickness, high precision and reduced blade wear, to support the drive to automation and a potential doubling of output.
The project will form one of the integral parts of a collaborative research grant with the industry, which is funded by the Technology Strategy Board. The candidate is expected to work as part of a multidisciplinary team.
Post-graduate qualification to doctorate level or significant equivalent experience at a senior level, some experience of research in high frequency devices such as ultrasonic device manufacture and/or control systems is essential. Knowledge of material modelling and use of commercial software packages is desirable, in the absence of which the candidate is expected to learn these skills during the course of the appointment.
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